EXPLICIT MOLECULAR DYNAMICS SIMULATION STUDIES TO DISCOVER NOVEL NATURAL COMPOUND ANALOGUES AS MYCOBACTERIUM TUBERCULOSIS INHIBITORS

Explicit molecular dynamics simulation studies to discover novel natural compound analogues as Mycobacterium tuberculosis inhibitors

Tuberculosis (TB) in one of the dreadful diseases present globally.This is caused by Mycobacterium tuberculosis.Mycobacterium tuberculosis dethiobiotin synthetase (MtDTBS) is an essential enzyme in biotin Smoothie biosynthesis and is an ideal target to design and develop novel inhibitors.In order to effectively combat this disease six natural compo

read more

NRF2 and Primary Cilia: An Emerging Partnership

When not dividing, many cell types target Hayward Puck Feeder Parts their centrosome to the plasma membrane, where it nucleates assembly of a primary cilium, an antenna-like signaling structure consisting of nine concentric microtubule pairs surrounded by membrane.Primary cilia play important pathophysiological roles in many tissues, their dysfunct

read more

Remarks to the risk assessment for abandoned mine sites

The authors give some remarks to the term risk regarding its use for the assessment of abandoned mine sites.These remarks are based on the recommendation Geotechnical Investigation and Evaluation of Abandoned Mine Sites developed by the working committee Abandoned Mining of the German Society for Geotechnical Engineering (DGGT) and the German Socie

read more